Clomid® is the commonly referenced brand name for the drug clomiphene citrate.
It is not an anabolic steroid, but a prescription drug generally prescribed to
women as a fertility aid. This is due to the fact that clomiphene citrate shows
a pronounced ability to stimulate ovulation. This is accomplished by
blocking/minimizing the effects of estrogen in the body. To be more specific
Clomid® is chemically a synthetic estrogen with both agonist/antagonist
properties, and is very similar in structure and action to Nolvadex®.
In certain target tissues it can block the ability of estrogen to bind with its
corresponding receptor. Its clinical use is therefore to oppose the negative
feedback of estrogens on the hypothalamic-pituitary-ovarian axis, which
enhances the release of LH and FSH. This of course can help to induce
For athletic purposes, Clomid® does not offer a tremendous benefit to women. In
men however, the elevation in both follicle stimulating hormone and (primarily)
luteinizing hormone will cause natural testosterone production to increase.
This effect is especially beneficial to the athlete at the conclusion of a
steroid cycle when endogenous testosterone levels are depressed. If endogenous
testosterone levels are not brought beck to normal, a dramatic loss in size and
strength is likely to occur once the anabolics have been removed. This is due
to the fact that without testosterone (or other androgens), the catabolic
hormone cortisol becomes the dominant force affecting muscle protein synthesis
(quickly bringing about a catabolic metabolism). Often referred to as the
post-steroid crash, it can quickly eat up much of your newly acquired muscle.
Clomid® can play a crucial role in preventing this crash in athletic
performance. As for women, the only real use for Clomid® is the possible
management of endogenous estrogen levels near contest time. This can increase
fat loss and muscularity, particularly in female trouble areas such as this
hips and thighs. Clomid® however often produces troubling side effects in women
(discussed below), and is likewise not in very high demand among this group of
Male users generally find that a daily intake of 50-100 mg (1-2 tablets) over a
four to six weefc period will bring testosterone production back to an
acceptable level. This raise in testosterone should occur slowly but evenly
throughout the period of intake. Since an immediate boost in testosterone is
often desirable, many prefer to combine Clomid® with HCG (Human Chorionic
Gonadotropin) for the first week or two after the steroids have been removed.
The kick-start from HCG also helps to restore the normal
ability for the testes to respond to endogenous LH, which may be hindered for
some time after the cycle is ended due to a prolonged state of inactivity. Once
the HCG is stopped, the user continues treatment with
Clomid® alone. HCG should not be used for longer than
two or three weeks though, as the resulting increased testosterone and estrogen
levels may again initiate negative feedback inhibition at the hypothalamus.
When planning your ancillary drug program, it is also important to remember
that injectable steroids can stay active for a long duration. Using ancillary
drugs the first week after a long acting injectable like Sustanon has been
stopped may prove to be wholly ineffective. Instead, the athlete should wait
for two to three weeks, to a point where androgen levels will be diminishing.
Here the body will be primed and ready to restore testosterone production.
Clomid® and HCG are also occasionally used periodically
during a steroid cycle, in an effort to prevent natural testosterone levels
from diminishing. In many instances this practice can prove difficult however,
especially when using strong androgens for longer periods of time. There is
also no exact method for using the two drugs in this manner. Some have
experimented by periodically administering small doses of HCG
along with one or two tablets of Clomid®, perhaps for a few days at a stretch
followed by a longer break. An on/off schedule would be implemented; for fear
that this combination may lose some effectiveness if used continuously for this
purpose. This method of intake may prove to be effective, although it is really
much more feasible to stimulate testosterone production after the cycle than to
try and maintain it for the long duration during.
In addition to helping with the post-cycle testosterone crash, this drug can
also help with elevated estrogen levels during a steroid cycle. A high estrogen
bevel puts an athlete in serious risk of developing gynecomastia, which is an
obvious unwanted side effect. With the intake of Clomid®, the athlete can
hopefully reduce his risk for developing gynecomastia. The estrogen "blocking"
properties of Clomid® appear to be slightly weaker than Nolvadex®
in comparison however, which is why it is not usually thought of as an equal
substitute for estrogen maintenance. Of course both drugs have similar actions
in the body. and are relatively interchangeable for this purpose. Clomid® can
likewise also be used as a maintenance anti-es!rogen throughout the duration of
steroid intake with good confidence, just as is done with Nolvadex®.
In most instances this will prove equally sufficient, the drug effectively
minimizing the activity of estrogen in the body and warding off gyno and excess
water/fat retention. Unfortunately just as with Nolvadex®
this is not always the case however, and many find it necessary to addition
another antiestrogenic drug. The most common adjunct is Proviron®,
an oral DHT used to competitively lower aromatase activity and raise the
androgen to estrogen ratio. The Clomid/Nolvadex and
Proviron® combination is extremely effective, although we could
alternately replace them both with a more specific aromatase inhibitor such as
Arimidex® or Cytadren®. While stronger at
combating estrogen in most cases, these drugs are also typically much more
As for toxicity and side effects, Clomid® is considered a very safe drug.
Bodybuilders seldom report any problems, but listed possible side effects do
include hot flashes, nausea, dizziness, headaches and temporarily blurred
vision. Such side effects usually only appear in females however, as they feel
the effects of estrogen manipulation much more readily than men. While female
athletes can clearly gain some benefit from this substance, estrogen
manipulation is probably not the most comfortable way to go about cutting up.
Should it still be used for such purposed and side effects do become
pronounced, the drug of course is to be discontinued and (at least) a break
taken from it.
Clomiphene citrate is widely available on the black market in a variety of brand
names. This substance can be expensive, often as high as $2-$4 per 50 mg tab.
Generics such as Clomiphene citrate by Anfarm in Greece are frequently seen on
the black market, and can sell for a considerably lower price. In the U.S.,
Omifin from Mexico appears to be most popular. Since there are no counterfeits
known to exist, Clomid® is considered a safe buy on the black market. Many
athletes prefer to purchase this item only from foreign mail-order sources,
always shopping for the lowest available tablet price.